This is the best kbase article of all time:
I would like more information about the Macintosh Portable used in the space shuttle by the NASA some years ago.
We believe you are referring to shuttle launch STS-43. The primary mission of STS-43 was to deploy a fourth TDRS satellite (Tracking and Data Relay Satellite). The shuttle was launched at 11:02 AM EST on Friday August 2, 1991, and landed at about 8:30 AM EST on Sunday August 11, 1991.
The shuttle carried a Macintosh Portable (nonbacklite) system on board. It was used for four primary purposes.
The Macintosh Portable was used to test using cursor control devices in low-gravity situations, send the first email from space, record medical information and help track the shuttle’s position in orbit.
There’s even a video of the machine ejecting a disk, sending it flying across a room aboard the shuttle.
Here’s a little more about the “WristMac” that is mentioned in the article.
Amazing stuff.