If you have a “flavored” (strawberry, tangerine, blueberry, lime or grape) iMac keyboard connected to your Intel-based Mac and you press the F12 key to eject a disc immediately after pressing the power button, you may experience a kernel panic. Intel-based Macs include iMac (Early 2006) and Mac mini (Early 2006).
Update to Mac OS X 10.4.9 to prevent this issue.
No word on if using the terrible iMac mouse would cause the same issue, because everyone rage destroyed them.